发明专利 Patents
9 项已授权发明专利，构建 DeepoMe 核心技术壁垒
Immunity assessment method, system and application based on pre-trained model
A method for assessing immunity using biological functions, applicable to predicting disease outcomes such as post-infection outcomes. The pre-trained model integrates multi-dimensional biomarker data including DNA methylation profiles, blood cell composition, and inflammatory markers to generate comprehensive immunity scores.
Method, system and application for generating compound intervention scheme based on pre-trained model
A method for generating personalized nutritional supplement combination intervention schemes using pre-trained network medicine models. The system analyzes individual molecular profiles and generates optimized compound combinations targeting specific biological pathways for personalized therapeutic interventions.
DNA methylation-based TCM syndrome quantitative characterization method, system and application
A method for quantitative characterization of traditional Chinese medicine (TCM) syndromes based on DNA methylation profiling. The system maps methylation patterns to TCM diagnostic categories, enabling objective measurement of syndromes and prediction of individual disease outcomes such as COVID-19 severity.
Methylation-based breast cancer risk prediction biomarkers, device, method and medium
Biomarkers, device, method and medium for breast cancer risk prediction based on methylation status of two gene sets combined with blood cell composition analysis. The method provides non-invasive breast cancer risk stratification using peripheral blood samples.
Depression screening and diagnosis biomarkers, device, method and medium
Biomarkers, device, method and medium for depression screening and diagnosis. The method calculates a methylation depression index based on DNA methylation feature values from peripheral blood, providing an objective screening tool for depression with AUC reaching 0.88.
Application of trans-anethole in preparation of anti-depression or depression prevention drugs
Application of trans-anethole in preparing anti-depression or depression prevention drugs. The compound shows significant antidepressant effects with low dosage requirements, rapid onset, and effective dose range of 0.1mg/kg to 210mg/kg.
AI-based TCM quality control and natural product efficacy prediction model and its construction and use method
An AI-based method for quality control of traditional Chinese medicine samples and efficacy prediction of natural products. The method quantifies the gap between TCM samples and their theoretical efficacy through chemical composition analysis and functional gene module targeting coefficients, using sparse autoencoder models for evaluation.
Primers and kit for detecting F2RL3 gene methylation in saliva and method of use
Primers and kit for detecting F2RL3 gene methylation in saliva using PCR amplification combined with mass spectrometry detection. The method evaluates the correlation between PM2.5 exposure and F2RL3 gene methylation levels in saliva, providing a non-invasive assessment method for the impact of airborne particulate matter on human health.
Drug virtual screening method and system based on receptor and ligand
A drug virtual screening method based on receptor and ligand interactions. The method includes obtaining target receptor activity data, constructing a ligand structure library, processing ligand activity data into molecular fingerprints, performing molecular docking and dynamics simulation, fusing molecular fingerprints with energy decomposition values, and building machine learning models for drug virtual screening.