团队论文 Team Publications

16 篇代表性论文(2006-2024)

Genome wide prediction of protein function via a generic knowledge discovery approach based on evidence integration

2006BMC Bioinformatics

Xiong J, Liu X, Chen Y

AI制药
systems biologyalgorithmprotein function predictionevidence integrationDOI

Pre-Clinical Drug Prioritization via Prognosis-Guided Genetic Interaction Networks

2010PLoS One

Xiong J, Zhou H, Wang L et al.

AI制药
machine learningdrug screeninggenetic interaction networkdrug repurposingDOI

Predicting response to preoperative chemotherapy agents by identifying drug action on modeled microRNA regulation networks

2014PLoS One

Xiong J, Li Y, Zhang M et al.

AI制药
precision medicinemachine learningchemotherapy responsemicroRNA regulation networkDOI

Circulating microRNAs Correlated with Bone Loss Induced by 45 Days of Bed Rest

2017Frontiers in Physiology

Xiong J, Liang F, Zhou X et al.

衰老研究
aerospace medicinebiomarkermicroRNAbone lossDOI

Integrated Analysis of DNA Methylation and Biochemical/Metabolic Parameter During the Long-Term Isolation Environment

2019Frontiers in Physiology

Xiong J, Chen Y, Wang L et al.

表观遗传学
aerospace medicineDNA methylationlong-term isolationmetabolic parameterDOI

Personalized Epigenome Remodeling Under Biochemical and Psychological Changes During Long-Term Isolation Environment

2019Frontiers in Physiology

Xiong J, Wang R, Liu F et al.

表观遗传学
aerospace medicineDNA methylationMars 500epigenome remodelingDOI

DNA Methylation Biomarkers Predict Objective Responses to PD-1/PD-L1 Inhibition Blockade

2019Frontiers in Genetics

Xiong J, Li Y, Zhang M et al.

表观遗传学
precision medicineDNA methylationPD-1/PD-L1immunotherapyDOI

Blood Cell DNA Methylation of Aging-Related Ubiquitination Gene DZIP3 Can Predict the Onset of Early Stage Colorectal Cancer

2020Frontiers in Oncology

Xiong J, Wang L, Chen Y et al.

表观遗传学
precision medicineearly cancer detectionDNA methylationDZIP3DOI

An agile discovery method of drugs for infectious diseases and tentative exploration of its application in drug discovery for COVID-19

2020Chinese Journal of Pharmacology and Toxicology

Xiong J, Zhou H, Wang L et al.

AI制药
computational pharmacologyAI drug screeningCOVID-19drug repurposing

Insulin-resistance and depression cohort data mining to identify nutraceutical related DNA methylation biomarker for type 2 diabetes

2020Genes & Diseases

Xiong J, Li Y, Zhang M et al.

表观遗传学
precision nutritionDNA methylationtype 2 diabetesinsulin resistanceDOI

Mining the Selective Remodeling of DNA Methylation in Promoter Regions to Identify Robust Gene-Level Associations with Phenotype

2021Frontiers in Molecular Biosciences

Xiong J, Wang L, Chen Y et al.

表观遗传学
precision medicineDNA methylationfeature extraction algorithmSIMPODOI

DNA Methylation Markers and Prediction Model for Depression and Their Contribution for Breast Cancer Risk

2022Frontiers in Molecular Neuroscience

Xiong J, Wang L, Chen Y et al.

表观遗传学
health monitoringdepressionbreast cancerDNA methylationDOI

Utilizing Pre-trained Network Medicine Models for Generating Biomarkers, Targets, Re-purposing Drugs, and Personalized Therapeutic Regimes: COVID-19 Applications

2023bioRxiv preprint

Xiong J, Wang L, Chen Y et al.

AI制药
network medicinedrug repurposingCOVID-19pre-trained modelDOI

Next Generation Aging Clock: A Novel Approach to Decoding Human Aging Through Over 3000 Cellular Pathways

2024bioRxiv preprint

Xiong J, Wang L, Chen Y

能力组学
aging clockcellular pathway3000 dimensionsDNA methylationDOI

AI-Generated Hallmarks of Aging and Cancer: A Computational Approach Using Causal Emergence and Dependency Networks

2024bioRxiv preprint

Xiong J, Wang L, Chen Y

根因医学
AIaging hallmarkscancercausal emergenceDOI

Capomics: A Novel Framework for Quantifying Human Intrinsic Capacity Through Multi-Dimensional DNA Methylation Profiling

2024bioRxiv preprint

Xiong J, Wang L, Chen Y et al.

能力组学
capability omicsintrinsic capacityDNA methylationmulti-dimensional profiling